{rfName}
Qu

Indexed in

License and use

Icono OpenAccess

Citations

9

Altmetrics

Analysis of institutional authors

Plaza, GuillermoAuthor

Share

Publications
>
Article

Quality of Life Impact of Hypoglossal Nerve Stimulation with Inspire (R) Device in Patients with Obstructive Sleep Apnea Intolerant to Continuous Positive Airway Pressure Therapy

Publicated to:Life. 12 (11): 1737- - 2022-11-01 12(11), DOI: 10.3390/life12111737

Authors: Baptista, P; Di Frisco, IM; Urrestarazu, E; Alcalde, J; Alegre, M; Sanchez, I; O'Connor-Reina, C; Plaza, G

Affiliations

Clin Univ Navarra, Pulmonol Dept, Pamplona 31007, Spain - Author
Hosp Quironsalud Marbella, Otorhinolaryngol Dept, Malaga 29603, Spain - Author
Univ Clin Navarra, Otorhinolaryngol Dept, Pamplona 31007, Spain - Author
Univ Hosp Fuenlabrada, Univ Rey Juan Carlos, Otorhinolaryngol Dept, Madrid 28042, Spain - Author

Abstract

Patients with obstructive sleep apnea (OSA) that do not tolerate/accept continuous positive airway pressure (CPAP) are candidates for surgical alternatives. Hypoglossal nerve stimulation (HNS) through the implantation of the Inspire (R) device constitutes a minimally invasive operative option. The main objective of this study is to estimate, under real-world clinical practice conditions, the 3-month impact on the quality of life (IQoL) of the HNS in patients with moderate/severe OSA who do not tolerate or accept CPAP, compared to patients who did not receive HNS. As a baseline, the unadjusted EuroQol utility index was 0.764 (SD:0.190) in the intervention group (IGr) and 0.733 (SD:0.205) in the control group (CGr); three months later, the indexes were 0.935 (SD: 0.101) and 0.727 (SD:0.200), respectively. The positive impact on quality of life was estimated to be +0.177 (95% CI: 0.044-0.310; p = 0.010). All dimensions in the IGr improved compared to CGr, especially for usual activities (p < 0.001) and anxiety/depression (p > 0.001). At the end of the follow-up, there was no significant difference in the quality of life between the general Spanish population and the IGr (difference: 0.012; CI95%: -0.03 to -0.057; p = 0.0578) for the same age range; however, there was a difference concerning the CGr (difference: -0.196; CI95%: -0.257 to -0.135; p < 0.001). In conclusion, patients with moderate/severe OSA implanted with the Inspire (R) device showed a positive IQoL.

Keywords

CpapEuroqol-5d-5lHypoglossal nerve stimulationHypopneaMinimally invasive surgical techniqueObstructive sleep apneaPopulationQuality of life

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Life due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2022, it was in position 34/92, thus managing to position itself as a Q2 (Segundo Cuartil), in the category Biology. Notably, the journal is positioned en el Cuartil Q2 para la agencia Scopus (SJR) en la categoría Paleontology.

From a relative perspective, and based on the normalized impact indicator calculated from the Field Citation Ratio (FCR) of the Dimensions source, it yields a value of: 2.07, which indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: Dimensions Jun 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-06-30, the following number of citations:

  • WoS: 3
  • Scopus: 6

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-06-30:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 19 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

    It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

    • The work has been submitted to a journal whose editorial policy allows open Open Access publication.

    Leadership analysis of institutional authors

    There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (Plaza Mayor, Guillermo).