{rfName}
Ho

Indexed in

License and use

Citations

Altmetrics

Grant support

Open Access funding enabled and organized by Projekt DEAL. The project leading to this application has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 896938 to ET. The project was further supported by research, network, and infrastructure Grants to KW (Carlsberg Foundation Grant Nos. CF15-0946 and CF20-0458, Independent Research Fund Denmark Grant No. 1026-00285B, Ministry of Science and Higher Education Denmark Grant No. 0192-00074B), and by research Grants to NM (JSPS KAKENHI Grant Nos. 18H04894 and 20 K06754).

Analysis of institutional authors

Herranz Matesanz, MaríaAuthorHerranz, MariaAuthor
Share
Publications
>
Article

Hooked on zombie worms? Genetic blueprints of bristle formation in Osedax japonicus (Annelida)

Publicated to:Evodevo. 15 (1): 7- - 2024-06-04 15(1), DOI: 10.1186/s13227-024-00227-1

Authors: Tilic, Ekin; Miyamoto, Norio; Herranz, Maria; Worsaae, Katrine

Affiliations

Rey Juan Carlos Univ, Super Sch Expt Sci & Technol ESCET, Area Biodivers & Conservat, Madrid, Spain - Author
Senckenberg Res Inst & Museum, Marine Zool Dept, Frankfurt, Germany - Author
Univ Copenhagen, Marine Biol Sect, Dept Biol, Copenhagen, Denmark - Author
X STAR, Japan Agcy Marine Earth Sci & Technol JAMSTEC, Yokosuka, Kanagawa, Japan - Author

Abstract

Background This study sheds light on the genetic blueprints of chaetogenesis (bristle formation), a complex biomineralization process essential not only for the diverse group of bristle worms (annelids) but also for other spiralians. We explore the complex genetic mechanisms behind chaetae formation in Osedax japonicus, the bone-devouring deepsea worm known for its unique ecological niche and morphological adaptations. Results We characterized the chaetal structure and musculature using electron microscopy and immunohistochemistry, and combined RNAseq of larval stages with in-situ hybridization chain reaction (HCR) to reveal gene expression patterns integral to chaetogenesis. Our findings pinpoint a distinct surge in gene expression during the larval stage of active chaetogenesis, identifying specific genes and cells involved. Conclusions Our research underscores the value of studying on non-model, "aberrant" organisms like Osedax, whose unique, temporally restricted chaetogenesis provided insights into elevated gene expression across specific larval stages and led to the identification of genes critical for chaetae formation. The genes identified as directly involved in chaetogenesis lay the groundwork for future comparative studies across Annelida and Spiralia, potentially elucidating the homology of chaetae-like chitinous structures and their evolution.

Keywords
BiomineralizationChaetaeChaetal arrangementChaetogenesisChitinChitin synthasChitin synthaseDiversityExpressionHooded hooksLarvaPositionSetaeSiboglinidaeUltrastructure

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Evodevo due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2024 there are still no calculated indicators, but in 2023, it was in position 9/54, thus managing to position itself as a Q1 (Primer Cuartil), in the category Evolutionary Biology.

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-18:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 5.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 3 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 4.
  • The number of mentions on the social network X (formerly Twitter): 4 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Denmark; Germany; Japan.